Selected Cruciferous Vegetables and their Effects on Azoxymethane (AOM) Induced Aberrant Crypt Foci
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چکیده
منابع مشابه
Chemopreventive effects of Strobilanthes crispus leaf extract on azoxymethane-induced aberrant crypt foci in rat colon
In this work, microscopic and histological studies suggest that Strobilanthes crispus ethanol extract reduce azoxymethane (AOM)-induced colonic aberrant crypt foci (ACF) in rats. S. crispus is considered a traditional medicine and used as an antioxidant. Its leaf contains a large amount of phenolic compounds to which its radical scavenging role is attributed and enhance its ability to eradicate...
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The modifying effects of dietary feeding with chrysin (5,7-dihydroxyflavone) on the development of azoxymethane (AOM)-induced colonic aberrant crypt foci (ACF) were investigated in male F344 rats. We also assessed the effect of chrysin on mitosis and apoptosis in 'normal appearing' crypts. To induce ACF, rats were given two weekly subcutaneous injections of AOM (20 mg/kg body weight). They also...
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Processed and red meat consumption is associated with the risk of colorectal cancer. Meta-analyses have suggested that the risk associated with processed meat is higher. Most processed meats are cured and cooked, which leads to formation of free nitrosyl heme. We speculated that free nitrosyl heme is more toxic than native myoglobin. The promoting effect of a freeze-dried, cooked, cured ham die...
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Andrographis paniculata is a grass-shaped medicinal herb, traditionally used in Southeast Asia. The aim of this study was to evaluate the chemoprotective effects of A. paniculata on colorectal cancer. A. paniculata ethanol extract was tested on azoxymethane (AOM)-induced aberrant crypt foci (ACF) in vivo and in vitro. A. paniculata treated groups showed a significant reduction in the number of ...
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colon polyps in familial adenomatosis polyposis (FAP) patients Department of Pathology, Center for Environmental Medicine, Medical (14–17). Hence, in both clinical and laboratory investigations, College of Ohio, 3000 Arlington Avenue, Toledo, OH 43614, USA NSAIDs appear to prevent the progression of precancerous 1To whom correspondence should be addressed lesions in the colon. Regression of pre...
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ژورنال
عنوان ژورنال: International Journal of Cancer Research
سال: 2012
ISSN: 1811-9727
DOI: 10.3923/ijcr.2012.95.104